How long, and then what.
Which compounds you continue, which you cycle, and how the day-90 decision is made.

Guide
7 min read
Which compounds you continue, which you cycle, which you take only as needed, and how the day-90 decision is made. A year, in 90-day blocks.
Why 90 days.
Long enough for every goal to show a number. Sleep and focus show in days, but body composition takes four to six weeks to move and twelve to be visible; skin takes eight to twelve; tissue keeps pace with the injury. Thirty days answers nothing for most goals. Ninety answers all of them, and it is short enough that stopping is a real choice and not a sunk cost.
It is also the unit the dose steps are built around. The core starts low and rises a step at a time, a month apart, so that by week twelve it is at the highest step the sheet allows, and you know how you respond at each one. The steps themselves are on the results sheet; this page is about what comes after them. The Planner draws the 90 days as a calendar, and the vial duration tool shows the week each vial ends.
Compounds you continue.
The fat-loss compound, for as long as the goal is fat loss. Stopping it returns appetite to where it was, and the weight tends to follow within months; the trials that produced the headline numbers ran for well over a year. At day 90 most people continue at the step they reached, and the conversation about higher steps happens then, not on a page.
The copper peptide, for skin and hair. Its effect is cumulative and it does not build a tolerance, so people who came for skin tend to keep it at the daily rhythm for as long as they want the result. NAD+, for energy, is continued at whatever rhythm the day-90 number supports, often three mornings a week for another block, then lighter.
See which of these belong in your protocol.
Get startedCompounds you cycle.
The growth hormone pairing. Ninety days on, then a break, then on again, because the body's own release is what it works with and a pause keeps that response fresh. The break is usually four to eight weeks, and the next block starts where the last one left off.
The repair peptides. Most recovery protocols either stop at day 90 or drop to a lighter rhythm, because tissue that has healed does not need daily help. If the injury is chronic, a maintenance rhythm continues; if it has resolved, the compound comes off. DSIP for sleep is judged on the tracked number at week eight and again at day 90; if deep sleep moved and holds when the dose is lightened, it is cycled down.
Compounds you take as needed.
The focus compounds. Semax and selank are same-day compounds: the effect peaks within hours and fades by evening, so there is nothing to cycle and nothing to taper. Most people settle at three or four days a week and skip the rest. The sheet builds in a week off in the last block to see whether the baseline itself has moved.
MOTS-c, the mitochondrial compound, is taken on training days and judged on training output. If capacity has not changed by week eight, it stops rather than rises. That is the general rule for every support compound: it earns its place or it comes off.
The day-90 decision.
Three outcomes, decided on the number. Continue: the number moved and the compound stays at the step it reached. Adjust: the core stays and the support is swapped, lightened or dropped. Stop: the number did not move, and the compound is not earning its place. The check-in is on the message thread, with the same person, and the next 90-day block is built from what the first one showed.
A year, then, looks like four blocks. The first is the one the quiz builds. The second usually continues the core and reconsiders the support. The third and fourth are where the cycled compounds come off and go back on. The timing answer sets out what each goal shows at each block. Take it to a doctor who knows you before you begin.
A year, in 90-day blocks.
Block 1, days 1 to 90
The protocol the quiz built. Core alone, then support at week five. Decide on the number at day 90.
Block 2, days 91 to 180
Continue the core at the step it reached. Reconsider the support. Cycled compounds take their first break.
Block 3, days 181 to 270
Cycled compounds return. Repair compounds have usually come off. As-needed compounds stay as needed.
Block 4, days 271 to 365
The year's number beside the first week's. The protocol is rebuilt from what the year showed.
The short version.
- Ninety days is long enough for every goal to show a number and short enough that stopping is a real choice.
- Continue: the fat-loss compound, the copper peptide, NAD+ at a lighter rhythm.
- Cycle: the growth hormone pairing, the repair peptides, DSIP once deep sleep holds.
- As needed: semax and selank, three or four days a week, with a week off built in.
- Every support compound earns its place by week eight or comes off.
- The decision at day 90 is continue, adjust, or stop, made on the number, with us.
- Take it to a doctor who knows you before you begin.
Three minutes. Built from your answers.
Get startedQuestions
How long should I take peptides?
In 90-day blocks. Some compounds continue for as long as the goal does, some cycle on and off, and some are taken only on the days that need them. This page lists which is which.
Do you cycle peptides?
Some. The growth hormone pairing and the repair peptides are cycled. The fat-loss compound and the copper peptide are continued. The focus compounds are as needed.
What happens if I stop the fat-loss compound?
Appetite returns to where it was and the weight tends to follow over months. That is why most people continue it at day 90 and why the protocol keeps the protein floor and the training in.
Do I keep raising the dose after 90 days?
That conversation happens at the day-90 check-in, on the number, and not on a page. The sheet stops at the highest step it allows on purpose.
Related
Longevity Manila builds your protocol from your answers. Fulfilment is by Primara Labs, our partner and supplier. Take it to a doctor who knows you before you begin.